Extracapsular extension breast

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Materials and Methods: Data from 2, women with breast cancer who underwent SLN biopsy were prospectively collected and retrospectively analyzed. Cancer-specific mortality and all-cause mortality were observed, calculated and multivariable analyses performed to identify significant interacting variables amongst demographics, clinical stage and pathological characteristics. Results: Thirty eight treated patients died from any cause and 12 died of cancer during the

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The presence of cancer cells is known as lymph node involvement. Lymph nodes are small, bean-shaped organs that act as filters along the lymph fluid channels. As lymph fluid leaves the breast and eventually goes back into the bloodstream, the lymph nodes try to catch and trap cancer cells before they reach other parts of the body.

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All patients underwent modified radical mastectomy MRM or wide excision with axillary node dissection. Axillary surgery consisted of level I-II dissection. All patients had pathological T1-T2 tumors.

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Please take this quick survey to tell us about what happens after you publish a paper. Breast Cancer Research and Treatment. Cox regression analysis was performed to correct for other prognostic factors.

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Marissa L. Vane Corresponding AuthorMaria A. Willemsen, Lori M.

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Gruber, B. Cole, M. Castiglione-Gertsch, S.

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The prognostic importance of extracapsular extension ECE in breast cancer is not yet clear, especially in patients with pathological T and N1 pTN1 disease. We aimed to investigate whether the extent of ECE was an independent prognostic factor for survival outcomes in patients with pTN1 breast cancer. A total number of patients with pTN1 breast cancer treated between and were retrospectively evaluated.

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Presence of lymph node LN metastasis is a strong prognostic factor in breast cancer, whereas the importance of extra-nodal extension and other nodal tumor features have not yet been fully recognized. Univariate survival analysis showed that several features of nodal metastases were associated with disease-free DFS or breast cancer specific survival BCSS. To conclude, the extent of ENE by its perpendicular diameter was independently prognostic and should be considered in line with nodal tumor burden in treatment decisions of node positive breast cancer.

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Extracapsular extension ECE of axillary metastases has importance as a risk factor for local or distant recurrence. Poorer survival in breast cancer has been suggested, but its prognostic value has not been uniformly confirmed. We selected

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Skip to search form Skip to main content. The significance of extracapsular extension of axillary lymph node metastases in early-stage breast cancer. Schnitt and Barbara J.

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